THE ULTIMATE GUIDE TO SBS88

The Ultimate Guide To sbs88

Some strands of Escherichia coli can have the polyketide synthetase (pks) island that encodes colibactin, a genotoxic compound which can alkylate DNA on adenine residues and induce point mutations with a selected signature12,13 (COSMIC SBS88). On top of that, publicity to pks+ E. coli generates a characteristic small indel signature (COSMIC ID18) w

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